2-Ketoglutaric acid
Cat. No.：YN374210
| 产品名称: | 2-Ketoglutaric acid |
| CAS No.: | 328-50-7 |
| Chemical Name: | 2-oxo-pentanedioic acid |
| Synonyms: | α-酮戊二酸; Alpha-Ketoglutaric acid |
| 分子量: | 146.10 |
| 分子式: | C₅H₆O₅ |
| SMILES: | OC(=O)CCC(=O)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 2-Ketoglutaric acid (Alpha-Ketoglutaric acid) 是 Krebs 循环中 ATP 或 GTP 产生的中间体。2-Ketoglutaric acid 还充当氮同化反应的主要碳骨架。2-Ketoglutaric acid 是酪氨酸酶(tyrosinase)的可逆抑制剂 (IC50=15 mM)。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Krebs, H.A., Salvin, E., and Johnson, W.A.The formation of citric and α-ketoglutaric acids in the mammalian bodyBiochem. J.32(1),113-117(1938)
Wu, N., Yang, M., Gaur, U., et al.Alpha-ketoglutarate: Physiological functions and applicationsBiomol. Ther. (Seoul)24(1),1-8(2016)
Liu, S., He, L., and Yao, K.The antioxidative function of alpha-ketoglutarate and its applicationsBiomed. Res. Int.,3408467(2018)
