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1,3-Dimethyluric acid

Cat. No.:YN374230

  • CAS No. :944-73-0

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    • 参考文献
    • 产品名称: 1,3-Dimethyluric acid
      CAS No.: 944-73-0
      Chemical Name: 7,9-dihydro-1,3-dimethyl-1H-purine-2,6,8(3H)-trione
      Synonyms:
      分子量:196.16
      分子式:C₇H₈N₄O₃
      SMILES:O=C(N1C)N(C)C2=C(NC(N2)=O)C1=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 1,3-Dimethyluric acid 是人体茶碱代谢的产物。1,3-Dimethyluric acid 是尿路结石中的嘌呤成分之一。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Cornish, H.H., and Christman, A.A.A study of the metabolism of theobromine, theophylline, and caffeine in manJ. Biol. Chem.228(1),315-323(1957)

      Caubet, M.-S., Elbast, W., Dubuc, M.-C., et al.Analysis of urinary caffeine metabolites by HPLC-DAD: The use of metabolic ratios to assess CYP1A2 enzyme activityJ. Pharm. Biomed. Anal.27(1-2),261-270(2002)

      Fuhr, U., Doehmer, J., Battula, N., et al.Biotransformation of methylxanthines in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms. Allocation of metabolic pathways to isoforms and inhibitory effects of quinolonesToxicology82(1-3),169-189(1993)

      Bhat, V.B., Sridhar, G.R., and Madyastha, K.M.Efficient scavenging of hydroxyl radicals and inhibition of lipid peroxidation by novel analogues of 1,3,7-trimethyluric acidLife Sci.70(4),381-393(2001)

      Psarra, T.A., Batzias, G.C., Peeters, T.L., et al.Theophylline and its metabolites produce a stimulating cholinergic effect on the small intestine and a nonadrenergic noncholinergic relaxing effect on the colon: A comparative study in the rabbit intestineJ. Vet. Pharmacol. Ther.30(6),541-519(2007)

      Yamamoto, K., Toyama, E., Kawakami, J., et al.Neurotoxic convulsions induced by theophylline and its metabolites in miceBiol. Pharm. Bull.19(6),869-872(1996)

      Safranow, K., and Machoy, Z.Methylated purines in urinary stonesClin. Chem.51(8),1493-1498(2005)

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