Paraxanthine
Cat. No.：YN374268
CAS No. ：611-59-6
| 产品名称: | Paraxanthine |
| CAS No.: | 611-59-6 |
| Chemical Name: | 3,7-dihydro-1,7-dimethyl-1H-purine-2,6-dione |
| Synonyms: | 1,7-二甲基黄嘌呤,1,7-DIMETHYLXANTHINE |
| 分子量: | 180.17 |
| 分子式: | C₇H₈N₄O₂ |
| SMILES: | O=C(N1C)NC2=C(N(C)C=N2)C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Paraxanthine，caffeine的代谢物，可通过刺激Ryanodine受体通道来抑制多巴胺能细胞的死亡。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Tassaneeyakul, W., Birkett, D.J., McManus, M.E., et al.Caffeine metabolism by human hepatic cytochromes P450: contributions of 1A2, 2E1 and 3A isoformsBiochem. Pharmacol.47(10),1767-1776(1994)
Chou, C.-C., and Vickroy, T.W.Antagonism of adenosine receptors by caffeine and caffeine metabolites in equine forebrain tissuesAm. J. Vet. Res.64(2),216-224(2003)
Orrú, M., Guitart, X., Karcz-Kubicha, M., et al.Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humansNeuropharmacology67,476-484(2013)
Okuro, M., Fujiki, N., Kotorii, N., et al.Effects of paraxanthine and caffeine on sleep, locomotor activity, and body temperature in orexin/ataxin-3 transgenic narcoleptic miceSleep33(7),930-942(2010)
