L-Homocitrulline
Cat. No.：YN374305
| 产品名称: | L-Homocitrulline |
| CAS No.: | 1190-49-4 |
| Chemical Name: | N6-(aminocarbonyl)-L-lysine |
| Synonyms: | 高瓜氨酸,Homocitrulline,Homo-L-citrulline |
| 分子量: | 189.21 |
| 分子式: | C₇H₁₅N₃O₃ |
| SMILES: | [H][C@](N)(CCCCNC(N)=O)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | L-Homocitrulline通过尿素循环途径获得的homoargininosuccinate代谢成高精氨酸 (homoarginine)，L-Homocitrulline的代谢异常会导致赖氨酸尿蛋白不耐受 (LPI)。 |
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Shi, J., Knevel, R., Suwannalai, P., et al.Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damageProc. Natl. Acad. Sci. USA108(42),17372-17377(2011)
Verbrugge, F.H., Tang, W.H.W., and Hazen, S.L.Protein carbamylation and cardiovascular diseaseKidney Int.88(3),474-478(2015)
Wang, Z., Nicholls, S.J., Rodriquez, E.R., et al.Protein carbamylation links inflammation, smoking, uremia and atherogenesisNat. Med.13(1),1176-1184(2007)
Mydel, P., Wang, Z., Brisslert, M., et al.Carbamylation-dependent activation of T cells: A novel mechanism in the pathogenesis of autoimmune arthritisJ. Immunol.184(12),6882-6890(2010)
