Phthalic acid mono-2-ethylhexyl ester
Cat. No.：YN374311
| 产品名称: | Phthalic acid mono-2-ethylhexyl ester |
| CAS No.: | 4376-20-9 |
| Chemical Name: | 1,2-benzenedicarboxylic acid, 1-(2-ethylhexyl) ester |
| Synonyms: | MEHP |
| 分子量: | 278.34 |
| 分子式: | C₁₆H₂₂O₄ |
| SMILES: | O=C(O)C1=CC=CC=C1C(OCC(CC)CCCC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Phthalic acid mono-2-ethylhexyl ester (MEHP) 是邻苯二甲酸二己酯 (DEHP) 的主要生物活性代谢物，可抑制 CYP17 的 17，20 裂合酶活性。 |
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Kratochvil, I., Hofmann, T., Rother, S., et al.Mono(2-ethylhexyl) phthalate (MEHP) and mono(2-ethyl-5-oxohexyl) phthalate (MEOHP) but not di(2-ethylhexyl) phthalate (DEHP) bind productively to the peroxisome proliferator-activated receptor γRapid Commun Mass Spectrom.33 Suppl. 1(Suppl. 1),75-85(2019)
Chiang, H.-c., Kuo, Y.-T., Shen, C.-C., et al.Mono(2-ethylhexyl)phthalate accumulation disturbs energy metabolism of fat cellsArch. Toxicol.90(3),589-601(2016)
Hsu, J.-W., Nien, C.-Y., Yeh, S.-C., et al.Phthalate exposure causes browning-like effects on adipocytes in vitro and in vivoFood Chem. Toxicol.142,111487(2020)
Aimuzi, R., Huang, S., Luo, K., et al.Levels and health risks of urinary phthalate metabolites and the association between phthalate exposure and unexplained recurrent spontaneous abortion: a large case-control study from ChinaEnviron. Res.212(Pt. C),113393(2022)
