7-Ketolithocholic acid
Cat. No.：YN374313
| 产品名称: | 7-Ketolithocholic acid |
| CAS No.: | 4651-67-6 |
| Chemical Name: | (3α,5β)-3-hydroxy-7-oxo-cholan-24-oic acid |
| Synonyms: | 3α-Hydroxy-7-oxo-5β-cholanic acid |
| 分子量: | 390.56 |
| 分子式: | C₂₄H₃₈O₄ |
| SMILES: | C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])C(C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) 是一种胆汁酸，可以被吸收，抑制内源性胆汁酸的产生和胆汁胆固醇的分泌。 |
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Fukiya, S., Arata, M., Kawashima, H., et al.Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives by Bacteroides intestinalis AM-1 isolated from human fecesFEMS Microbiol. Lett.293(2),263-270(2009)
Fromm, H., Carlson, G.L., Hofmann, A.F., et al.Metabolism in man of 7-ketolithocholic acid: Precursor of cheno- and ursodeoxycholic acidsAm. J. Physiol.239(3),G161-G166(1980)
Kanai, S., Sato, Y., Nokubo, M., et al.Hepatic biotransformation and choleretic effect of 7-ketolithocholic acid in the ratLipids24(10),859–865(1989)
Zhao, Y.Y., Cheng, X.L., Wei, F., et al.Application of faecal metabonomics on an experimental model of tubulointerstitial fibrosis by ultra performance liquid chromatography/high-sensitivity mass spectrometry with MSE data collection techniqueBiomarkers17(8),721-729(2012)
Cao, H., Huang, H., Xu, W., et al.Fecal metabolome profiling of liver cirrhosis and hepatocellular carcinoma patients by ultra performance liquid chromatography-mass spectrometryAnal. Chim. Acta.691(1-2),68-75(2011)
