Lanosterol
Cat. No.：YN374328
CAS No. ：79-63-0
| 产品名称: | Lanosterol |
| CAS No.: | 79-63-0 |
| Chemical Name: | lanosta-8,24-dien-3β-ol |
| Synonyms: | 羊毛甾醇 |
| 分子量: | 426.72 |
| 分子式: | C₃₀H₅₀O |
| SMILES: | C[C@]12C3=C(CC[C@@]1([C@]([C@H](C)CC/C=C(C)/C)([H])CC2)C)[C@@]4([C@@](C(C)([C@@H](O)CC4)C)([H])CC3)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lanosterol 是胆固醇合成的中间产物，Lanosterol 可诱导胆固醇合成的速率控制酶 HMG-CoA 还原酶的泛素化和降解。Lanosterol 抑制与神经退行性疾病相关的错误折叠蛋白的聚集和细胞毒性。 |
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Warrilow, A.G., Melo, N., Martel, C.M., et al.Expression, purification, and characterization of Aspergillus fumigatus sterol 14-a demethylase (CYP51) isoenzymes A and BAntimicrob. Agents Chemother.54(10),4225-4234(2010)
Zhao, L., Chen, X.J., Zhu, J., et al.Lanosterol reverses protein aggregation in cataractsNature523(7562),607-611(2015)
Asami, T., Mizutani, M., Shimada, U., et al.Triadimefon, a fungicidal triazole-type P450 inhibitor, induces brassinosteroid deficiency-like phenotypes in plants and binds to DWF4 protein in the brassinosteroid biosynthesis pathwayBiochem. J.369 (Pt 1),71-76(2003)
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