Nebentan potassium
Cat. No.：YN320312
CAS No. ：342005-82-7
| 产品名称: | Nebentan potassium |
| CAS No.: | 342005-82-7 |
| Chemical Name: | |
| Synonyms: | YM598 |
| 分子量: | 529.61 |
| 分子式: | C₂₄H₂₀KN₅O₅S |
| SMILES: | O=S(/C=C/C1=CC=CC=C1)([N-]C2=NC(C3=NC=CC=N3)=NC(OC)=C2OC4=CC=CC=C4OC)=O.[K+] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nebentan potassium (YM598) 是一种有效的具有口服活性的非肽类内皮素受体 (ETAreceptor) 拮抗剂，通过 Bosentan (HY-A0013) 修饰得到。Nebentan potassium 抑制 [125I] 内皮素-1 与人内皮素 ETA和 ETB受体结合，Ki分别为 0.697 nM 和 569 nM。Nebentan potassium 可用于改善肺心病和心肌梗死的相关研究。 |
| IC50和靶点: | [{name:"ETA:0.679 nM (Ki)"},{name: "ETB:569 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
