Tezosentan
Cat. No.：YN321118
CAS No. ：180384-57-0
| 产品名称: | Tezosentan |
| CAS No.: | 180384-57-0 |
| Chemical Name: | N-[6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-(1-methylethyl)-2-pyridinesulfonamide; |
| Synonyms: | RO 610612 |
| 分子量: | 605.63 |
| 分子式: | C₂₇H₂₇N₉O₆S |
| SMILES: | O=S(C1=NC=C(C(C)C)C=C1)(NC2=NC(C3=CC(C4=NNN=N4)=NC=C3)=NC(OCCO)=C2OC5=CC=CC=C5OC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tezosentan (RO 610612) 是内皮素(ET)受体的一个拮抗剂，其对 ETA和 ETB受体的pA2值分别为 9.5,7.7。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Clozel, M., et al.: J. Pharmacol. Exp. Ther., 290, 840 (1999), Dingemanse, J., et al.: Br. J. Clin. Pharmacol., 53, 355 (2002), Schalcher, C., et al.: Am. Heart J., 142, 340 (2001),
