EIDD-1931
Cat. No.：YN250360
CAS No. ：3258-02-4
| 产品名称: | EIDD-1931 |
| CAS No.: | 3258-02-4 |
| Chemical Name: | uridine, 4-oxime |
| Synonyms: | β-D-N4-hydroxycytidine; NHC |
| 分子量: | 259.22 |
| 分子式: | C₉H₁₃N₃O₆ |
| SMILES: | O=C1N=C(NO)C=CN1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) 是一种核苷类物质，是一种有效的抗病毒试剂 (anti-virus agent)。EIDD-1931 有效抑制委内瑞拉马脑炎病毒 (VEEV)、基孔肯亚病毒 (CHIKV) 和丙型肝炎病毒 (HCV) 的复制活性。 |
| IC50和靶点: | |
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Yoon, J.-J., Toots, M., Lee, S., et al.Orally efficacious broad-spectrum ribonucleoside analog inhibitor of influenza and respiratory syncytial virusesAntimicrob. Agents Chemother.62(8),e00766-00718(2018)
Urakova, N., Kuznetsova, V., Crossman, D.K., et al.β-ᴅ-N4-Hydroxycytidine Is a potent anti-alphavirus compound that induces a high level of mutations in the viral genomeJ. Virol.92(3),e01965-01917(2018)
Barnard, D.L., Day, C.W., Bailey, K., et al.Evaluation of immunomodulators, interferons and known in vitro SARS-coV inhibitors for inhibition of SARS-coV replication in BALB/c miceAntivir. Chem. Chemother.17(5),275-784(2006)
Sheahan, T.P., Sims, A.C., Zhou, S., et al.An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in miceSci. Transl. Med.12(541),eabb5883(2020)
