Pleconaril
Cat. No.：YN250827
CAS No. ：153168-05-9
| 产品名称: | Pleconaril |
| CAS No.: | 153168-05-9 |
| Chemical Name: | 3-[3,5-dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole |
| Synonyms: | VP 63843; Win 63843 |
| 分子量: | 381.35 |
| 分子式: | C₁₈H₁₈F₃N₃O₃ |
| SMILES: | FC(C1=NC(C2=CC(C)=C(OCCCC3=CC(C)=NO3)C(C)=C2)=NO1)(F)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pleconaril 是一种衣壳抑制剂, 有潜力用于肠病毒的研究。 Pleconaril 有效抑制复制, IC50值为 50 nM。 |
| IC50和靶点: | |
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Florea, N.R., Maglio, D., and Nicolau, D.P.Pleconaril, a novel antipicornaviral agentPharmacotherapy23(3),339-348(2003)
Bernard, A., Lacroix, C., Cabiddu, M.G., et al.Exploration of the anti-enterovirus activity of a series of pleconaril/pirodavir-like compoundsAntivir. Chem. Chemother.24(2),56-61(2015)
Bernard, A., Lacroix, C., Cabiddu, M.G., et al.Exploration of the anti-enterovirus activity of a series of pleconaril/pirodavir-like compoundsAntivir. Chem. Chemother.24(2),56-61(2015)
Zhang, G., Zhou, F., Gu, B., et al.In vitro and in vivo evaluation of ribavirin and pleconaril antiviral activity against enterovirus 71 infectionArch. Virol.157(4),669-679(2012)
