Vomifoliol
Cat. No.:YN380349
产品名称: | Vomifoliol |
CAS No.: | 1649450-12-3 |
Chemical Name: | 4-methoxy-N-[[3-(1-methylethyl)-5-isoxazolyl]methyl]-3-[(1-methyl-4-piperidinyl)oxy]-benzamide |
Synonyms: | VU-0476201 |
分子量: | 387.5 |
分子式: | C21H29N3O4 |
SMILES: | CN1CCC(OC2=C(OC)C=CC(C(NCC3=CC(C(C)C)=NO3)=O)=C2)CC1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ML352 是突触前胆碱转运体(CHT) 的非竞争性抑制剂,对于表达人 CHT 和小鼠前脑突触体的 HEK293细胞,其Ki值分别为 92 nM 和 166 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Ennis, E.A., Wright, J., Retzlaff, C.L., et al.Identification and characterization of ML352: A novel, noncompetitive inhibitor of the presynaptic choline transporterACS Chem. Neurosci.6(3),417-427(2015)