GSK6853
Cat. No.：YN310004
CAS No. ：1910124-24-1
| 产品名称: | GSK6853 |
| CAS No.: | 1910124-24-1 |
| Chemical Name: | N-[2,3-dihydro-1,3-dimethyl-6-[(2R)-2-methyl-1-piperazinyl]-2-oxo-1H-benzimidazol-5-yl]-2-methoxy-benzamide |
| Synonyms: | GSK6853;GSK-6853;GSK 6853 |
| 分子量: | 409.48 |
| 分子式: | C₂₂H₂₇N₅O₃ |
| SMILES: | C[C@@H]1CNCCN1C2=C(NC(C3=CC=CC=C3OC)=O)C=C(C(N4C)=C2)N(C)C4=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK6853 是一个强的和有选择性的RPF1乙酰赖氨酸抑制剂 (pKd=9.5)，它的选择性是其它的乙酰赖氨酸的 1600 倍。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Bamborough, P., Barnett, H.A., Becher, I., et al.GSK6853, a chemical probe for inhibition of the BRPF1 bromodomainACS Med. Chem. Lett.7(6),552-557(2016)
