BI-7273
Cat. No.：YN310007
CAS No. ：1883429-21-7
| 产品名称: | BI-7273 |
| CAS No.: | 1883429-21-7 |
| Chemical Name: | 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-2,7-naphthyridin-1(2H)-one |
| Synonyms: | |
| 分子量: | 353.41 |
| 分子式: | C₂₀H₂₃N₃O₃ |
| SMILES: | CN(C)CC1=C(OC)C=C(C(C2=C3C=NC=C2)=CN(C)C3=O)C=C1OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BI-7273 是一种选择性的，细胞透过的BRD9抑制剂，IC50和Kd分别为 19 和 0.75 nM；同时对 BRD7 的作用较强，IC50和Kd值分别为 117 nM 和 0.3 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Martin, L.J., Koegl, M., Bader, G., et al.Structure-based design of an in vivo active selective BRD9 inhibitorJ. Med. Chem.59(10),4462-4475(2016)
