GSK 4027
Cat. No.：YN310034
CAS No. ：2079896-25-4
| 产品名称: | GSK 4027 |
| CAS No.: | 2079896-25-4 |
| Chemical Name: | 4-bromo-2-methyl-5-[[(3R,5R)-1-methyl-5-phenyl-3-piperidinyl]amino]-3(2H)-pyridazinone |
| Synonyms: | GSK 4027;GSK-4027 |
| 分子量: | 377.28 |
| 分子式: | C₁₇H₂₁BrN₄O |
| SMILES: | BrC1=C(N[C@@H]2C[C@H](C3=CC=CC=C3)CN(C)C2)C=NN(C)C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK 4027 是一种PCAF/GCN5溴结构域的化学探针，作用于 PCAF，pIC50为 7.4±0.11。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Humphreys, P.G., Bamborough, P., Chung, C.W., et al.Discovery of a potent, cell penetrant, and selective p300/CBP-associated factor (PCAF)/general control nonderepressible 5 (GCN5) bromodomain chemical probeJ. Med. Chem.60(2),695-709(2017)
