BAY-299
Cat. No.：YN310081
CAS No. ：2080306-23-4
| 产品名称: | BAY-299 |
| CAS No.: | 2080306-23-4 |
| Chemical Name: | 2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3(2H)-dione |
| Synonyms: | BAY 299,BAY299 |
| 分子量: | 429.47 |
| 分子式: | C₂₅H₂₃N₃O₄ |
| SMILES: | O=C(N1C2=C(C)C=C(N(C)C3=O)C(N3C)=C2)C4=CC=C(CCCO)C5=C4C(C1=O)=CC=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BAY-299 是一种非常有效的双重抑制剂，抑制BRPF2溴结构域 (BD)，TAF1 BD2，和TAF1L BD2，IC50分别为 67 nM，8 nM 和 106 nM。 |
| IC50和靶点: | [{name:"BRPF2 BD:67 nM (IC50)"},{name: "BRPF1 BD:3150 nM (IC50)"},{name: "BRPF3 BD:5550 nM (IC50)"},{name: "TAF1 BD2:8 nM (IC50)"},{name: "TAF1L BD2:106 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Pérez-Salvia, M., and Esteller, M.Bromodomain inhibitors and cancer therapy: From structures to applicationsEpigenetics,(2016)
