FL-411
Cat. No.：YN310107
CAS No. ：2118944-88-8
| 产品名称: | FL-411 |
| CAS No.: | 2118944-88-8 |
| Chemical Name: | 5,6,7,8-tetrahydro-2-(4-hydroxy-3,5-dimethylphenyl)-7-methyl-pyrido[4′,3′:4,5]thieno[2,3-d]pyrimidin-4(1H)-one |
| Synonyms: | BRD4-IN-1 |
| 分子量: | 341.43 |
| 分子式: | C₁₈H₁₉N₃O₂S |
| SMILES: | CN1CCC2=C(SC(N=C(C3=CC(C)=C(O)C(C)=C3)N4)=C2C4=O)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | FL-411 是一种有效的选择性BRD4抑制剂，抑制BRD4(1)，IC50为 0.43±0.09 μM。 |
| IC50和靶点: | [{name:"BRD4(1):0.43 μM (IC50)"}] |
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| Solvent & Solubility: |
Ouyang, L., Zhang, L., Liu, J., et al.Discovery of a small-molecule bromodomain-containing protein 4 (BRD4) inhibitor that induces AMP-activated protein kinase-modulated autophagy-associated cell death in breast cancerJ. Med. Chem.60(24),9990-10012(2017)
