SGC-iMLLT
Cat. No.：YN310136
CAS No. ：2255338-25-9
| 产品名称: | SGC-iMLLT |
| CAS No.: | 2255338-25-9 |
| Chemical Name: | 1-methyl-N-[2-[[(2S)-2-methyl-1-pyrrolidinyl]methyl]-1H-benzimidazol-6-yl]-1H-indazole-5-carboxamide |
| Synonyms: | |
| 分子量: | 388.47 |
| 分子式: | C₂₂H₂₄N₆O |
| SMILES: | CN1N=CC2=CC(C(NC3=CC=C(NC(CN4[C@@H](C)CCC4)=N5)C5=C3)=O)=CC=C21 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SGC-iMLLT 是一种领先的化学探针，也是一种有效选择性的MLLT1/3-histone互作抑制剂，IC50值为 0.26 μM。SGC-iMLLT 对 MLLT1 YEATS 域 (YD) 和 MLLT3 YD (AF9/YEATS3) 具有高结合力，Kd值分别为 0.129 和 0.077 μM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Moustakim, M., Christott, T., Monteiro, O.P., et al.Discovery of an MLLT1/3 YEATS domain chemical probeAngew. Chem. Int. Ed. Engl.57(50),16302-16307(2018)
