GNE-207
Cat. No.：YN310148
| 产品名称: | GNE-207 |
| CAS No.: | 2158266-58-9 |
| Chemical Name: | |
| Synonyms: | GNE207;GNE 207 |
| 分子量: | 510.59 |
| 分子式: | C₂₉H₃₀N₆O₃ |
| SMILES: | O=C(NC)C1=NC=C(C2=CC3=C(C=N2)C(C4=NN(C5CCOCC5)C6=C4CN(C(C)=O)CC6)=CC=C3)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GNE-207 是一种有效、选择性、可口服的CBP溴结构域抑制剂，IC50值为 1 nM，对其选择性是的 BRD4 (1) 的 2500 多倍。在 MV-4-11 细胞中，GNE-207 对MYC表达具有高效活性，EC50值为 18 nM。 |
| IC50和靶点: | [{name:"BRD4(1):3.1 μM (IC50)"},{name: "CBP:1 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
