MS645
Cat. No.：YN310179
CAS No. ：2250091-96-2
| 产品名称: | MS645 |
| CAS No.: | 2250091-96-2 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 938.04 |
| 分子式: | C₄₈H₅₄Cl₂N₁₀O₂S₂ |
| SMILES: | O=C(NCCCCCCCCCCNC(C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1)=O)C[C@H]5C6=NN=C(C)N6C7=C(C(C)=C(C)S7)C(C8=CC=C(Cl)C=C8)=N5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MS645 是一种BET bromodomains (BrD)抑制剂，对于 BRD4-BD1/BD2 的 Ki值为 18.4 nM。MS645 在空间上限制 BRD4 BrDs 的二价抑制，从而导致实体肿瘤细胞中 BRD4 转录活性的持续抑制。 |
| IC50和靶点: | [{name:"BRD4(BD1BD2):18.4 nM (Ki)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
