MS436
Cat. No.:YN310252
CAS No. :1395084-25-9
产品名称: | MS436 |
CAS No.: | 1395084-25-9 |
Chemical Name: | MS 436; |
Synonyms: | MS-436; MS 436 |
分子量: | 383.42 |
分子式: | C₁₈H₁₇N₅O₃S |
SMILES: | O=S(C1=CC=C(/N=N/C2=CC(C)=C(O)C=C2N)C=C1)(NC3=NC=CC=C3)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MS436 是一种bromodomain抑制剂,有效作用于 BRD4 BrD1,Ki为 30-50 nM,比作用于 BrD2 选择性高 10 倍。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Gallenkamp, D. et al.: ChemMedChem, 9, 438 (2014)
Zhang, G. et al.: J. med. Chem., 56, 9251 (2013)