I-BRD9
Cat. No.：YN310313
CAS No. ：1714146-59-4
| 产品名称: | I-BRD9 |
| CAS No.: | 1714146-59-4 |
| Chemical Name: | 5-ethyl-4,5-dihydro-4-oxo-N-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)-7-[3-(trifluoromethyl)phenyl]-thieno[3,2-c]pyridine-2-carboximidamide |
| Synonyms: | GSK602 |
| 分子量: | 497.55 |
| 分子式: | C₂₂H₂₂F₃N₃O₃S₂ |
| SMILES: | N=C(C(S1)=CC2=C1C(C3=CC=CC(C(F)(F)F)=C3)=CN(CC)C2=O)NC(CC4)CCS4(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | I-BRD9是第一个选择性的BRD9细胞化学探针(pIC 50= 7.3)。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Muller, S., Filippakopoulos, P., and Knapp, S.Bromodomains as therapeutic targetsExpert Rev. Mol. Med.13,e29(2011)
Theodoulou, N.H., Bamborough, P., Bannister, A.J., et al.Discovery of I-BRD9, a selective cell active chemical probe for bromodomain containing protein 9 inhibitionJ. Med. Chem.59(4),1425-1439(2015)
