I-CBP112
Cat. No.：YN310323
| 产品名称: | I-CBP112 |
| CAS No.: | 1640282-31-0 |
| Chemical Name: | 1-[7-(3,4-dimethoxyphenyl)-2,3-dihydro-9-[[(3S)-1-methyl-3-piperidinyl] methoxy]-1,4-benzoxazepin-4(5H)-yl]-1-propanone |
| Synonyms: | I-CBP 112;(S)-1-(7-(3,4-dimethoxyphenyl)-9-((1-methylpiperidin-3-yl)methoxy)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)propan-1-one;1-[7-(3,4-Dimethoxyphenyl)-9-[[(3S)-1-methylpiperidin-3-yl]methoxy]-2,3,4,5-tetrahydro-1,4-benzoxazepin-4-yl]propan-1-one;1 |
| 分子量: | 468.59 |
| 分子式: | C₂₇H₃₆N₂O₅ |
| SMILES: | COC1=C(OC)C=C(C2=CC(OC[C@H]3CCCN(C)C3)=C(OCCN(C(CC)=O)C4)C4=C2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | I-CBP112是一种特异性和有效的乙酰-赖氨酸竞争性蛋白-蛋白相互作用抑制剂，抑制CBP/p300溴结构域，增强 p300 的乙酰化作用。 |
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| Solvent & Solubility: |
Picaud, S., Fedorov, O., Thanasopoulou, A., et al.Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapyCancer Res.75(23),5106-5119(2015)
