GCN2-IN-6
Cat. No.：YN290238
CAS No. ：2183470-09-7
| 产品名称: | GCN2-IN-6 |
| CAS No.: | 2183470-09-7 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 485.29 |
| 分子式: | C₁₉H₁₂Cl₂F₂N₄O₃S |
| SMILES: | O=S(C1=CC(Cl)=CC(CO)=C1Cl)(NC2=CC=C(F)C(C#CC3=CN=C(N)N=C3)=C2F)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GCN2-IN-6 (Compound 6d) 是一种有效的口服GCN2抑制剂，通过酶法 (IC50为 1.8 nM) 和细胞分析 (IC50为 9.3 nM) 证实。GCN2-IN-6 还是 eIF2α 激酶PERK抑制剂，IC50为 0.26 nM (酶法测定) 和 230 nM (细胞测定)。 |
| IC50和靶点: | |
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| Clinical Trial: | |
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