(Z)-4EGI-1
Cat. No.:YN290470
CAS No. :901787-88-0
产品名称: | (Z)-4EGI-1 |
CAS No.: | 901787-88-0 |
Chemical Name: | |
Synonyms: | |
分子量: | 451.28 |
分子式: | C₁₈H₁₂Cl₂N₄O₄S |
SMILES: | O=C(O)/C(CC1=CC=CC=C1[N+]([O-])=O)=N/NC2=NC(C3=CC=C(Cl)C(Cl)=C3)=CS2.[(Z)] |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (Z)-4EGI-1 是 4EGI-1 的 Z-型异构体,是eIF4E/eIF4G相互作用和翻译起始的抑制剂。(Z)-4EGI-1 有效结合eIF4E,IC50为 43.5 μM,Kd值为 8.74 μM。(Z)-4EGI-1 具有抗癌活性。 |
IC50和靶点: | |
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Clinical Trial: | |
Solvent & Solubility: |