Biochanin A
Cat. No.：YN372213
| 产品名称: | Biochanin A |
| CAS No.: | 491-80-5 |
| Chemical Name: | 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | 4-Methylgenistein; Olmelin |
| 分子量: | 284.26 |
| 分子式: | C₁₆H₁₂O₅ |
| SMILES: | OC1=C2C(OC=C(C3=CC=C(OC)C=C3)C2=O)=CC(O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Biochanin A 是一种天然存在的脂肪酸酰胺水解酶 (FAAH) 抑制剂，抑制FAAH，作用于小鼠，大鼠，人 FAAH，IC50分别为 1.8，1.4 和 2.4 μM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Evans, B.A., Griffiths, K., and Morton, M.S.Inhibition of 5α-reductase in genital skin fibroblasts and prostate tissue by dietary lignans and isoflavonoidsJ. Endocrinol.147(2),295-302(1995)
Khan, S.I., Zhao, J., Khan, I.A., et al.Potential utility of natural products as regulators of breast cancer-associated aromatase promotersReprod. Biol. Endocrinol.9:91,(2011)
Patisaul, H.B., and Jefferson, W.The pros and cons of phytoestrogensFront. Neuroendocrinol.31(4),400-419(2010)
Wang, L., Waltenberger, B., Pferschy-Wenzig, E.M., et al.Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): A reviewBiochem. Pharmacol.92(1),73-89(2014)
Rasbach, K.A., and Schnellmann, R.G.Isoflavones promote mitochondrial biogenesisJ. Pharmacol. Exp. Ther.325(2),536-543(2008)
Thors, L., Burston, J.J., Alter, B.J., et al.Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolaseBr. J. Pharmacol.160(3),549-560(2010)
Medjakovic, S., and Jungbauer, A.Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptorJ. Steroid Biochem. Mol. Biol.108(1-2),171-177(2008)
