JZL195
Cat. No.:YN372273
CAS No. :1210004-12-8
产品名称: | JZL195 |
CAS No.: | 1210004-12-8 |
Chemical Name: | 4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carboxylate |
Synonyms: | JZL 195;JZL-195;4-[(3-Phenoxyphenyl)methyl]-1-piperazinecarboxylic acid 4-nitrophenyl ester;JZL195 |
分子量: | 433.46 |
分子式: | C₂₄H₂₃N₃O₅ |
SMILES: | O=C(OC1=CC=C([N+]([O-])=O)C=C1)N(CC2)CCN2CC3=CC(OC4=CC=CC=C4)=CC=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | JZL195 是一种有效选择的脂肪酸酰胺水解酶(FAAH)和单酰甘油脂肪酶(MAGL)双重抑制剂,IC50s 分别为 2 和 4 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Long, J.Z., Nomura, D.K., Vann, R.E., et al.Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivoProc. Natl. Acad. Sci. USA106(48),20270-20275(2009)