JNJ-42165279
Cat. No.:YN372561
产品名称: | JNJ-42165279 |
CAS No.: | 1346528-50-4 |
Chemical Name: | N-(4-chloro-3-pyridinyl)-4-[(2,2-difluoro-1,3-benzodioxol-5-yl)methyl]-1-piperazinecarboxamide |
Synonyms: | JNJ-5279 |
分子量: | 410.80 |
分子式: | C₁₈H₁₇ClF₂N₄O₃ |
SMILES: | O=C(N1CCN(CC2=CC=C(OC(F)(F)O3)C3=C2)CC1)NC4=C(Cl)C=CN=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | JNJ-42165279是FAAH抑制剂, 抑制 hFAAH和 rFAAH, IC50分别为70±8 nM 和 313 ± 28 nM。 |
IC50和靶点: | |
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Keith, J.M., Jones, W.M., Tichenor, M., et al.Preclinical characterization of the FAAH inhibitor JNJ-42165279ACS Med. Chem. Lett.6(12),1204-1208(2015)