JNJ-37822681 dihydrochloride
Cat. No.：YN1730038
| 产品名称: | JNJ-37822681 dihydrochloride |
| CAS No.: | 2108806-02-4 |
| Chemical Name: | N-[1-[(3,4-difluorophenyl)methyl]-4-piperidinyl]-6-(trifluoromethyl)-3-pyridazinamine, dihydrochloride |
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| 分子量: | 445.26 |
| 分子式: | C₁₇H₁₉Cl₂F₅N₄ |
| SMILES: | FC(C1=NN=C(NC2CCN(CC3=CC=C(F)C(F)=C3)CC2)C=C1)(F)F.Cl.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JNJ-37822681 dihydrochloride 是一种高效、特异性、有中枢活性的，能快速解离的多巴胺 D2受体拮抗剂，对多巴胺 D2L受体的亲和力适中 (Ki=158 nM)，具有研究精神分裂症和躁郁症的潜力。 |
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Langlois, X., Megens, A., Lavreysen, H., et al.Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophreniaJ. Pharmacol. Exp. Ther.342(1),91-105(2012)
