GSK2256098
Cat. No.：YN440016
CAS No. ：1224887-10-8
规格
价格(RMB)
库存
| 产品名称: | GSK2256098 |
| CAS No.: | 1224887-10-8 |
| Chemical Name: | 2-[[5-chloro-2-[[3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl]amino]-4-pyridinyl]amino]-N-methoxy-benzamide |
| Synonyms: | GTPL7939 |
| 分子量: | 414.89 |
| 分子式: | C₂₀H₂₃ClN₆O₂ |
| SMILES: | O=C(NOC)C1=CC=CC=C1NC2=CC(NC3=CC(C)=NN3C(C)C)=NC=C2Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GSK2256098 是一种选择性FAK激酶抑制剂，可抑制胰腺癌细胞的生长和存活。 |
| IC50和靶点: | |
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Zhang, J., He, D.H., Zajack-Kaye, M., et al.A small molecule FAK kinase inhibitor, GSK2256098, inhibits growth and survival of pancreatic ductal adenocarcinoma cellsCell Cycle13(19),3143-3149(2014)
Thanapprapasr, D., Previs, R.A., Hu, W., et al.PTEN expression as a predictor of response to focal adhesion kinase inhibition in uterine cancerMol. Cancer. Ther.14(16),1466-1475(2015)
