Fisogatinib
Cat. No.：YN440015
CAS No. ：1707289-21-1
规格
价格(RMB)
库存
| 产品名称: | Fisogatinib |
| CAS No.: | 1707289-21-1 |
| Chemical Name: | N-[(3S,4S)-3-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]tetrahydro-2H-pyran-4-yl]-2-propenamide |
| Synonyms: | BLU-554 |
| 分子量: | 503.38 |
| 分子式: | C₂₄H₂₄Cl₂N₄O₄ |
| SMILES: | C=CC(N[C@@H]1[C@H](NC2=NC=C3C=C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)C=CC3=N2)COCC1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fisogatinib (BLU-554) 是一种有效的高选择性口服的FGFR4抑制剂，其IC50值为 5 nM。Fisogatinib 在依赖FGFR4信号传导的肝细胞癌 (HCC) 模型中具有显着的抗肿瘤活性。 |
| IC50和靶点: | [{name:"FGFR4:5 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Bifulco, N., Jr., DiPietro, L.V., Hodous, B.L., et al.Inhibitors of the fibroblast growth factor receptor,(2015)
