TG 100572 Hydrochloride
Cat. No.:YN440047
产品名称: | TG 100572 Hydrochloride |
CAS No.: | 867331-64-4 |
Chemical Name: | |
Synonyms: | TG100572 Hydrochloride;TG-100572 Hydrochloride |
分子量: | 512.43 |
分子式: | C₂₆H₂₇Cl₂N₅O₂ |
SMILES: | ClC1=CC=C(O)C=C1C2=CC(C)=C(N=C(NC(C=C3)=CC=C3OCCN4CCCC4)N=N5)C5=C2.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TG 100572 Hydrochloride 是多靶点激酶抑制剂,抑制受体酪氨酸激酶 (receptor tyrosine kinases) 和Src激酶 (Src kinases); 对VEGFR1,VEGFR2,FGFR1,FGFR2,PDGFRβ,Fgr,Fyn,Hck,Lck,Lyn,Src,Yes 的IC50值分别为2,7,2,16,13,5,0.5,6,0.1,0.4,1,0.2 nM。 |
IC50和靶点: | [{name:"VEGFR1:2 nM (IC50)"},{name: "VEGFR2:7 nM (IC50)"},{name: "FGFR1:2 nM (IC50)"},{name: "FGFR2:16 nM (IC50)"},{name: "PDGFRβ:13 nM (IC50)"}] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |