TG 100801
Cat. No.：YN440049
CAS No. ：867331-82-6
规格
价格(RMB)
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| 产品名称: | TG 100801 |
| CAS No.: | 867331-82-6 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 580.08 |
| 分子式: | C₃₃H₃₀ClN₅O₃ |
| SMILES: | O=C(C1=CC=CC=C1)OC2=CC=C(Cl)C(C3=CC(C)=C(N=C(NC(C=C4)=CC=C4OCCN5CCCC5)N=N6)C6=C3)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TG 100801 是TG 100572的前药，通过去酯化产生TG 100572，开可用于黄斑变性的研究。TG 100572 是多靶点激酶抑制剂，抑制受体酪氨酸激酶 (receptor tyrosine kinases) 和Src激酶 (Src kinases); 对VEGFR1，VEGFR2，FGFR1，FGFR2，PDGFRβ，Fgr，Fyn，Hck，Lck，Lyn，Src，Yes 的IC50值分别为2，7，2，16，13，5，0.5，6，0.1，0.4，1，0.2。 |
| IC50和靶点: | [{name:"VEGFR1:2 nM (IC50)"},{name: "VEGFR2:7 nM (IC50)"},{name: "FGFR1:2 nM (IC50)"},{name: "FGFR2:16 nM (IC50)"},{name: "PDGFRβ:13 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
