ENMD-2076
Cat. No.:YN440131
产品名称: | ENMD-2076 |
CAS No.: | 934353-76-1 |
Chemical Name: | |
Synonyms: | ENMD 2076; ENMD2076 |
分子量: | 375.47 |
分子式: | C₂₁H₂₅N₇ |
SMILES: | CC1=CC(NC2=NC(/C=C/C3=CC=CC=C3)=NC(N4CCN(CC4)C)=C2)=NN1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ENMD-2076是多靶点激酶抑制剂,抑制Aurora A,Flt3,KDR/VEGFR2,Flt4/VEGFR3,FGFR1,FGFR2,Src,PDGFRα的IC50值分别为1.86,14,58.2,15.9,92.7,70.8,20.2 and 56.4 nM。 |
IC50和靶点: | [{name:"Aurora A:14 nM (IC50)"},{name: "KDR:58.2 nM (IC50)"},{name: "Flt-4:15.9 nM (IC50)"},{name: "FGFR1:92.7 nM (IC50)"},{name: "FGFR2:70.8 nM (IC50)"},{name: "PDGFRα:56.4 nM (IC50)"},{name: "Flt3:1.86 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |