CP-547632 hydrochloride
Cat. No.:YN440262
产品名称: | CP-547632 hydrochloride |
CAS No.: | 252003-71-7 |
Chemical Name: | |
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分子量: | 568.86 |
分子式: | C₂₀H₂₅BrClF₂N₅O₃S |
SMILES: | O=C(NC1=C(C(N)=O)C(OCC2=C(F)C=C(Br)C=C2F)=NS1)NCCCCN3CCCC3.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | CP-547632 hydrochloride 是一种口服有效的,ATP 竞争性的VEGFR-2和FGF激酶抑制剂,IC50分别为 11 nM 和 9 nM。CP-547632 hydrochloride 对 VEGFR2 和 bFGF 的选择性高于 EGFR,PDGFRβ 和相关的酪氨酸激酶 (TKs)。CP-547632 hydrochloride 具有抗肿瘤作用。 |
IC50和靶点: | [{name:"VEGFR-2:11 nM (IC50)"},{name: "FGFR:9 nM (IC50)"}] |
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