Infigratinib phosphate
Cat. No.：YN440266
CAS No. ：1310746-10-1
规格
价格(RMB)
库存
| 产品名称: | Infigratinib phosphate |
| CAS No.: | 1310746-10-1 |
| Chemical Name: | |
| Synonyms: | BGJ-398 phosphate; NVP-BGJ398 phosphate |
| 分子量: | 658.47 |
| 分子式: | C₂₆H₃₄Cl₂N₇O₇P |
| SMILES: | O=P(O)(O)O.ClC1=C(C(Cl)=C(C=C1OC)OC)NC(N(C2=CC(NC3=CC=C(C=C3)N4CCN(CC4)CC)=NC=N2)C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Infigratinib phosphate (BGJ-398 phosphate; NVP-BGJ398 phosphate) 是FGFR抑制剂，对 FGFR1，FGFR2 和 FGFR3 的IC50分别为0.9，1.4 和 1 nM，比对 FGFR4 和 VEGFR2 的抑制性高40倍，对 Abl，Fyn，Kit，Lck 和 Lyn几乎无活性。 |
| IC50和靶点: | [{name:"FGFR1:0.9 nM (IC50)"},{name: "FGFR2:1.4 nM (IC50)"},{name: "FGFR3:1 nM (IC50)"},{name: "FGFR4:60 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
