AZD4547
Cat. No.：YN440268
CAS No. ：1035270-39-3
规格
价格(RMB)
库存
| 产品名称: | AZD4547 |
| CAS No.: | 1035270-39-3 |
| Chemical Name: | rel-N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-4-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-benzamide |
| Synonyms: | ABSK 091 |
| 分子量: | 463.57 |
| 分子式: | C₂₆H₃₃N₅O₃ |
| SMILES: | C[C@H](C1)N[C@@H](C)CN1C2=CC=C(C(NC3=NNC(CCC4=CC(OC)=CC(OC)=C4)=C3)=O)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AZD4547 是一种有效的FGFR家族抑制剂，作用于FGFR1，FGFR2，FGFR3和FGFR4，IC50分别为 0.2 nM，2.5 nM，1.8 nM 和 165 nM。 |
| IC50和靶点: | [{name:"FGFR1:0.2 nM (IC50)"},{name: "FGFR2:2.5 nM (IC50)"},{name: "FGFR3:1.8 nM (IC50)"},{name: "FGFR4:165 nM (IC50)"}] |
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| Solvent & Solubility: |
Gavine, P.R., Mooney, L., Kilgour, E., et al.AZD4547: An orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase familyCancer Res.72(8),2045-2056(2012)
