Lucitanib
Cat. No.:YN440315
产品名称: | Lucitanib |
CAS No.: | 1058137-23-7 |
Chemical Name: | |
Synonyms: | 德立替尼; E-3810 |
分子量: | 443.49 |
分子式: | C₂₆H₂₅N₃O₄ |
SMILES: | O=C(NC)C1=CC=CC2=C1C=CC(OC3=CC=NC4=CC(OCC5(N)CC5)=C(OC)C=C43)=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Lucitanib (E-3810) 是VEGFR和FGFR的双重抑制剂,有效和选择性地抑制VEGFR1,VEGFR2,VEGFR3,FGFR1,FGFR2,IC50分别为7 nM,25 nM,10 nM,17.5 nM,82.5 nM。 |
IC50和靶点: | [{name:"VEGFR1:7 nM (IC50)"},{name: "VEGFR2:25 nM (IC50)"},{name: "VEGFR3:10 nM (IC50)"},{name: "FGFR1:17.5 nM (IC50)"},{name: "FGFR2:82.5 nM (IC50)"}] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |