Formononetin
Cat. No.:YN440422
产品名称: | Formononetin |
CAS No.: | 485-72-3 |
Chemical Name: | 7-hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
Synonyms: | 刺芒柄花素; Biochanin B; Flavosil; Formononetol |
分子量: | 268.26 |
分子式: | C₁₆H₁₂O₄ |
SMILES: | O=C1C(C2=CC=C(OC)C=C2)=COC3=CC(O)=CC=C13 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Formononetin (Formononetol; Flavosil)提取自红三叶草,能剂量依赖的抑制DU-145/PC-3细胞增殖。 |
IC50和靶点: | [{name:"FGFR2:4.31 μM (IC50)"}] |
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Patisaul, H.B., and Jefferson, W.The pros and cons of phytoestrogensFront. Neuroendocrinol.31(4),400-419(2010)
Medjakovic, S., and Jungbauer, A.Red clover isoflavones biochanin A and formononetin are potent ligands of the human aryl hydrocarbon receptorJ. Steroid Biochem. Mol. Biol.108(1-2),171-177(2008)
Yang, Y., Zhao, Y., Ai, X., et al.Formononetin suppresses the proliferation of human non-small cell lung cancer through induction of cell cycle arrest and apoptosisInt. J. Clin. Exp. Pathol.7(12),8453-8461(2014)
Wang, H., Zhang, D., Ge, M., et al.Formononetin inhibits enterovirus 71 replication by regulating COX-2/PGE2 expressionVirol. J.12,35(2015)