Shield-1
Cat. No.：YN330115
| 产品名称: | Shield-1 |
| CAS No.: | 914805-33-7 |
| Chemical Name: | 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-,(1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-(4-morpholinyl)ethoxy]phenyl]propyl ester, (2S)-2-Piperidinecarboxylic Acid; |
| Synonyms: | Shld1 |
| 分子量: | 748.90 |
| 分子式: | C₄₂H₅₆N₂O₁₀ |
| SMILES: | O=C([C@H]1N(C([C@H](C2=CC(OC)=C(OC)C(OC)=C2)CC)=O)CCCC1)O[C@@H](C3=CC=CC(OCCN4CCOCC4)=C3)CCC5=CC=C(OC)C(OC)=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Shield-1 是特异性，细胞可渗透的，高亲和力 FK506 结合蛋白-12 (FKBP) 配体，通过与突变的 FKBP (mtFKBP) 结合而逆转其不稳定性，允许 mtFKBP 融合蛋白的条件表达。Shield-1 可以稳定整个融合蛋白。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Thomas, Christian., et al.: Mol Cancer Ther,В 12,В 2342 (2013)
