KB02-SLF
Cat. No.：YN330229
CAS No. ：2384184-40-9
| 产品名称: | KB02-SLF |
| CAS No.: | 2384184-40-9 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 949.52 |
| 分子式: | C₅₀H₆₅ClN₄O₁₂ |
| SMILES: | O=C([C@H]1N(C(C(C(C)(C)CC)=O)=O)CCCC1)O[C@@H](C2=CC=CC(NC(CCOCCOCCNC(COC3=CC4=C(N(C(CCl)=O)CCC4)C=C3)=O)=O)=C2)CCC5=CC=C(OC)C(OC)=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | KB02-SLF 是一种基于 PROTAC 的核FKBP12降解剂 (molecular glue)。KB02-SLF 通过共价修饰 DCAF16 (E3 ligase) 促进FKBP12降解，并可以提高生物系统中蛋白质降解的持久性。KB02-SLF 由 SLF 与泛素 E3 连接酶配体 (KB02) 通过 linker 连接而成。 |
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