Gilteritinib
Cat. No.:YN440210
产品名称: | Gilteritinib |
CAS No.: | 1254053-43-4 |
Chemical Name: | 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide |
Synonyms: | ASP2215 |
分子量: | 552.71 |
分子式: | C₂₉H₄₄N₈O₃ |
SMILES: | NC(C1=NC(CC)=C(NC2CCOCC2)N=C1NC3=CC(OC)=C(N4CCC(N5CCN(C)CC5)CC4)C=C3)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Gilteritinib 是一种有效的FLT3/AXL抑制剂,IC50分别为 0.29 nM/0.73 nM。 |
IC50和靶点: | |
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Solvent & Solubility: |
Lee, L.Y., Hernandez, D., Rajkhowa, T., et al.Preclinical studies of gilteritinib, a next-generation FLT3 inhibitorBlood129(2),257-260(2017)