Rivaroxaban
Cat. No.：YN372646
| 产品名称: | Rivaroxaban |
| CAS No.: | 366789-02-8 |
| Chemical Name: | 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide |
| Synonyms: | 利伐沙班; BAY 59-7939 |
| 分子量: | 435.88 |
| 分子式: | C₁₉H₁₈ClN₃O₅S |
| SMILES: | O=C(N(C1=CC=C(N2C(COCC2)=O)C=C1)C3)O[C@H]3CNC(C4=CC=C(S4)Cl)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rivaroxaban 是一种高效，选择性直接的凝血因子 Xa (FXa) 抑制剂，IC50为 0.7 nM，Ki为 0.4 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Turpie, A.G.G.Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseasesArterioscler. Thromb. Vasc. Biol.27(6),1238-1247(2007)
Babilonia, K., and Trujillo, T.The role of prothrombin complex concentrates in reversal of target specific anticoagulantsThromb. J.12:8,(2014)
Turpie, A.G.G.Rivaroxaban as an oral anticoagulant for stroke prevention in atrial fibrillationTher. Clin. Risk Manag.10,197-205(2014)
