AZD4320
Cat. No.：YN270116
CAS No. ：1357576-48-7
| 产品名称: | AZD4320 |
| CAS No.: | 1357576-48-7 |
| Chemical Name: | |
| Synonyms: | AZD4320 |
| 分子量: | 945.53 |
| 分子式: | C₄₅H₄₈ClF₃N₄O₇S₃ |
| SMILES: | O=C(NS(=O)(C1=CC=C(N[C@H](CCN(CCO)C)CSC2=CC=CC=C2)C(S(=O)(C(F)(F)F)=O)=C1)=O)C3=CC=C(N4CCC([C@H](C5=CC=CC=C5C6=CC=C(Cl)C=C6)O)CC4)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AZD4320 是 BH-3 的新型类似物，有效的BCL2/BCLxL的双重抑制剂。AZD4320 对于 KPUM-MS3，KPUM-UH1，和 STR-428 细胞系的IC50分别为 26 nM，17 nM，和 170 nM。 |
| IC50和靶点: | [{name:"BCL2:17 nM (IC50, KPUM-UH1 cells)"},{name: "BCLxL:17 nM (IC50, KPUM-UH1 cells)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
