S55746
Cat. No.:YN270132
CAS No. :1448584-12-0
产品名称: | S55746 |
CAS No.: | 1448584-12-0 |
Chemical Name: | |
Synonyms: | BLC201 |
分子量: | 710.82 |
分子式: | C₄₃H₄₂N₄O₆ |
SMILES: | O=C(C1=C2CCCCN2C(C3=C(C(N4CC5=C(C=CC=C5)C[C@H]4CN6CCOCC6)=O)C=C(OCO7)C7=C3)=C1)N(C8=CC=C(O)C=C8)C9=CC=CC=C9 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | S55746 (BLC201) 是一种有效、可口服、选择性的BCL-2抑制剂,其Ki值和Kd值分别为 1.3 nM 和 3.9 nM。S55746 (BLC201) 具有抗肿瘤活性且毒性低。 |
IC50和靶点: | [{name:"Bcl-2:1.3 nM (Ki)"},{name: "Bcl-xL:520 nM (Ki)"},{name: "Bcl-2:3.9 nM (Kd)"},{name: "Bcl-xL:186 nM (Kd)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |