(R)-(-)-Gossypol acetic acid
Cat. No.：YN270306
| 产品名称: | (R)-(-)-Gossypol acetic acid |
| CAS No.: | 866541-93-7 |
| Chemical Name: | |
| Synonyms: | (R)-(-)-醋酸棉酚; AT-101 (acetic acid); (-)-Gossypol acetic acid; (R)-Gossypol acetic acid |
| 分子量: | 578.61 |
| 分子式: | C₃₂H₃₄O₁₀ |
| SMILES: | OC1=C2C(C=O)=C(O)C(O)=C(C(C)C)C2=CC(C)=[C@]1[C@]3=C(C)C=C4C(C(C)C)=C(O)C(O)=C(C=O)C4=C3O.CC(O)=O.[R] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | (R)-(-)-Gossypol acetic acid (AT-101 (acetic acid)) 是天然产物 Gossypol 的左旋异构体。AT-101 结合到Bcl-2，Mcl-1和Bcl-xL蛋白，Ki值分别为 260±30 nM，170±10 nM 和 480±40 nM。 |
| IC50和靶点: | [{name:"Mcl-1:170 nM (Ki)"},{name: "Bcl-2:260 nM (Ki)"},{name: "Bcl-xL:480 nM (Ki)'}, 'Autophagy'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
