Maritoclax
Cat. No.：YN1441160
CAS No. ：1227962-62-0
| 产品名称: | Maritoclax |
| CAS No.: | 1227962-62-0 |
| Chemical Name: | 1,1′-(4,4′,5,5′-tetrachloro[1,3′-bi-1H-pyrrole]-2,2′-diyl)bis[1-(2-hydroxyphenyl)-methanone |
| Synonyms: | Marinopyrrole A |
| 分子量: | 510.15 |
| 分子式: | C₂₂H₁₂Cl₄N₂O₄ |
| SMILES: | OC1=CC=CC=C1C(C2=C(N3C(C(C4=CC=CC=C4O)=O)=CC(Cl)=C3Cl)C(Cl)=C(Cl)N2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Maritoclax (Marinopyrrole A) 是一种新颖的Mcl-1特异性抑制剂，IC50值为 10.1 μM，对 BCL-xl 的 IC50值 > 80 μM。 |
| IC50和靶点: | [{name:"Mcl-1:10.1 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Nicolaou, K.C., Simmons, N.L., Chen, J.S., et al.Total synthesis and biological evaluation of marinopyrrole A and analoguesTetrahedron Lett.52(17),2041-2043(2011)
