Gossypol (acetic acid)
Cat. No.：YN1441161
| 产品名称: | Gossypol (acetic acid) |
| CAS No.: | 12542-36-8 |
| Chemical Name: | 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde Acetic Acid; 1,1',6,6',7,7'-Hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde Acetic Acid; (±)-Gossypol Acetic |
| Synonyms: | 醋酸棉酚; (±)-Gossypol-acetic acid; BL-193 (acetic acid) |
| 分子量: | 578.61 |
| 分子式: | C₃₂H₃₄O₁₀ |
| SMILES: | OC1=C(C2=C(O)C(C(C=O)=C(O)C(O)=C3C(C)C)=C3C=C2C)C(C)=CC4=C(C(C)C)C(O)=C(O)C(C=O)=C41.O=C(O)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Gossypol acetic acid ((±)-Gossypol-acetic acid) 是一种从棉籽和根中分离出来的天然产物，分别与Bcl-xL蛋白和Bcl-2蛋白结合，Ki值分别为 0.5-0.6 μM 和 0.2-0.3 mM。 |
| IC50和靶点: | [{name:"Bcl-xL:0.5-0.6 μM (Ki)"},{name: "Bcl-2:0.2-0.3 mM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Huo, M. et al.: Int. Immunopharmacol., 15, 442 (2013)
Coutinho, E. et al.: Contraception. 65, 259 (2002)
Royer, R. et al.: J. Med. Chem., 29, 1799 (1986)
