FIN56
Cat. No.:YN270047
CAS No. :1083162-61-1
产品名称: | FIN56 |
CAS No.: | 1083162-61-1 |
Chemical Name: | N2,N7-dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide |
Synonyms: | FIN56,FIN-56 ,FIN 56 |
分子量: | 517.66 |
分子式: | C₂₅H₃₁N₃O₅S₂ |
SMILES: | O=S(C1=CC(/C2=N\O)=C(C3=C2C=C(S(=O)(NC4CCCCC4)=O)C=C3)C=C1)(NC5CCCCC5)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | FIN56 是一种特异性的铁死亡 (ferroptosis) 诱导剂。FIN56 通过诱导 GPX4 降解来诱导铁死亡。FIN56 还结合并激活角鲨烯合酶。 |
IC50和靶点: | |
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Solvent & Solubility: |
Shimada, K., Skouta, R., Kaplan, A., et al.Global survey of cell death mechanisms reveals metabolic regulation of ferroptosisNat. Chem. Biol.12(7),497-503(2016)