Liproxstatin-1
Cat. No.：YN270197
CAS No. ：950455-15-9
| 产品名称: | Liproxstatin-1 |
| CAS No.: | 950455-15-9 |
| Chemical Name: | N-[(3-chlorophenyl)methyl]-spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine |
| Synonyms: | Liproxstatin-1;N-[(3-Chlorophenyl)methyl]-spiro[piperidine-4,2′(1′H)-quinoxalin]-3′-amine;N-[(3-chlorophenyl)methyl]spiro[4H-quinoxaline-3,4′-piperidine]-2-amine;Liproxstatin 1;BCP15985;DNDI1417503;s7699;AK548157;J3.631.135E;N-(3-Chlorobenzyl)-1'H-spiro[p |
| 分子量: | 340.85 |
| 分子式: | C₁₉H₂₁ClN₄ |
| SMILES: | ClC1=CC(CNC2=NC3=CC=CC=C3NC24CCNCC4)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Liproxstatin-1 是一种有效的ferroptosis抑制剂，抑制 ferroptotic 细胞死亡 (IC50=22 nM)。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Friedmann Angeli, J.P., Schneider, M., Proneth, B., et al.Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in miceNat. Cell. Biol.16(12),1180-1191(2014)
Zilka, O., Shah, R., Li, B., et al.On the mechanism of cytoprotection by ferrostatin-1 and liproxstatin-1 and the role of lipid peroxidation in ferroptotic cell deathACS Cent. Sci.3(3),232-243(2017)
